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Current Scenario and Challenges in Clinical Diagnosis of Colorectal Serrated Lesions from A Perspective of Aggressive Treatment Yoshihiro Kishida 1 , Kinichi Hotta 1 , Kenichiro Imai 1 , Sayo Ito 1 , Hiroyuki Ono 1 1Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan Keyword: 大腸鋸歯状病変 , hyperplastic polyp , sessile serrated lesion , sessile serrated lesion with dysplasia , 内視鏡診断 pp.1579-1587
Published Date 2020/12/25
DOI https://doi.org/10.11477/mf.1403202205

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  • Abstract
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 Serrated lesions are classified into HP(hyperplastic polyp), SSL(sessile serrated lesion), and TSA(traditional serrated adenoma). Their rates of malignant transformation differ from each other. Thus, these lesions need to be differentiated and assessed for the presence of dysplasia or cancer before selecting the resection target and determining treatment method. In this study, we examined≥10-mm HP, SSL, and those with dysplasia or cancer resected at our hospital to identify diagnostically useful findings. As the lesion size increased, greater proportions were accounted for lesions classified as SSL and lesions with dysplasia or cancer. No endoscopic findings were useful to differentiate between HP and SSL. The following findings were significantly associated with the lesions with dysplasia or cancer:lesion size, double elevation, and neoplastic JNET(types 2A, 2B, and 3). Particularly, the diagnostic value of lesions with dysplasia or cancer was greater when the lesion size was ≥15mm and double elevation or neoplastic JNET were identified.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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