Gastrointestinal Lesions of Behçet-like Disease Observed in Trisomy 8 Yusuke Honzawa 1 , Yuki Hayashi 1 , Hiroki Kitamoto 1 , Makoto Okabe 1 , Satoshi Yamada 1 , Shuji Yamamoto 1 , Hiroshi Seno 1 1Department of Gastroenterology and Hepatology, Kyoto University Hospital, Kyoto, Japan Keyword: 骨髄異形成症候群 , MDS , 染色体異常 , trisomy 8 , Behçet病 , 消化管潰瘍 , 予後不良 pp.1702-1708
Published Date 2019/12/25
DOI https://doi.org/10.11477/mf.1403201901
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 MDS(myelodysplastic syndrome)is a hematologic disease characterized by peripheral cytopenia and ineffective hematopoiesis in the bone marrow and often complicated with autoimmune diseases. MDS with chromosome 8 abnormality(trisomy 8)demonstrates gastrointestinal lesions characteristic of Behçet's disease or Behçet-like diseases. The clinical features of gastrointestinal lesions in MDS with trisomy 8 are different from those of gastrointestinal lesions without trisomy 8, and the prognosis is generally considered to be poor. In this report, we describe the clinical features and characteristics of Behçet-like gastrointestinal lesions with trisomy 8-positive MDS based on recent reports and our own cases.

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