Intervals in Colorectal Cancer Screening and Surveillance after Polypectomy:Results from the Japan Polyp Study Kinichi Hotta 1 , Takahisa Matsuda 2,3 , Takahiro Fujii 4 , Yasushi Sano 5 , Shin-ei Kudo 6 , Yasushi Oda 7 , Hiroaki Ikematsu 8 , Nozomu Kobayashi 9 , Hirokazu Taniguchi 10 , Yutaka Saito 3 1Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan 2Division of Screening Technology, Center for Public Health Sciences, National Cancer Center, Tokyo 3Endoscopy Division, National Cancer Center Hospital, Tokyo 4TF Clinic, Tokyo 5GI Center, Sano Hospital, Kobe, Japan 6Digestive Disease Center, Showa University, Northern Yokohama Hospital, Yokaohama, Japan 7Oda Clinic, Kumamoto, Japan 8Division of Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan 9Division of Gastroenterology, Tochigi Cancer Center, Utsunomiya, Japan 10Pathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo Keyword: 大腸癌 , 大腸ポリープ , スクリーニング , サーベイランス pp.1190-1195
Published Date 2017/8/25
DOI https://doi.org/10.11477/mf.1403201150
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 RCTs(Randomized controlled trials)have not revealed a role of colonoscopy in preventing CRC(colorectal cancer)-related deaths. However, large-scale cohort studies have provided strong evidences regarding the effectiveness of colonoscopy in preventing CRC-related deaths. In the United States, colonoscopy is recommended as one of the screening tests for CRC, and an interval of 10 years is suggested after a negative colonoscopy. There have been some recent promising on-going RCTs of screening using colonoscopy, with CRC-related deaths as the primary endpoint. In western countries, surveillance guidelines after polyp removal were published according to the stratification of individual risks. Therefore, creating a Japanese surveillance guideline, such as that by the Japan Polyp Study, on the basis of evidences from clinical trials that include Japanese patients is important.

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