Gastric Ulcer Caused by Syphilis Infection, Report of a Case Yasutaka Morimoto 1 , Tomoki Nakajima 1 , Nobuhiro Fukuda 2 , Akihiro Obora 2 , Takao Kojima 2 , Nobuaki Yagi 2 , Shigeyuki Sugie 3 , Takahiro Kato 4 1Department of Gastroenterology, Saiseikai Kyoto Hospital, Nagaokakyo, Japan 2Department of Gastroenterology, Murakami Memorial Hospital of Asahi University, Gifu, Japan 3Department of Pathology, Murakami Memorial Hospital of Asahi University, Gifu, Japan 4Department of Gastroenterology, Aiseikai Yamashina Hospital, Kyoto, Japan Keyword: 胃梅毒 , 第2期 , 漏斗状狭窄 , 性感染症 pp.939-944
Published Date 2017/6/25
DOI https://doi.org/10.11477/mf.1403201111
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 Recently, cases of syphilis infection have been increasingly reported in Japan because of the diversification of the sexual lifestyle. We present a typical case of gastric syphilis and discuss its endoscopic and radiographic features by reviewing the related literature. A 27-year-old man presented to our clinic with epigastric pain. Endoscopic examination showed multiple erosions and shallow ulcers with irregular margins at the angle and antrum, which were accompanied by pus production and slight wall rigidity that was more pronounced at the area close to the pyloric ring. Upper gastrointestinal series with barium meal showed uneven barium adhesion to the mucosa and slight rigidity of the gastric wall, which formed funnel-shaped stenosis. These typical images along with his blood test being serologically positive for syphilis led us to suspect gastric syphilis. We pathologically confirmed the diagnosis by detecting Treponema pallidum in the biopsied specimen. After treatment with ampicillin for 1 month, the condition of the ulcer significantly improved and was recognized as a small ulcer scar at the angle. The knowledge of these characteristic images of gastric syphilis has important value for the differential diagnosis of gastric syphilis and other morphologically similar diseases.

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