Differential Diagnosis between Gastric Syphilis and Scirrhous Carcinoma of the Stomach Hiroyuki Kobayashi 1 , Yuji Sakai 2 , Kouichi Kurahara 2 , Tadahiko Fuchigami 2 1Institute of Gastroenterology, Fukuoka Sanno Hospital, Fukuoka, Japan 2Institute of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan Keyword: 胃梅毒 , 第2期梅毒 , 梅毒性胃粘膜疹 , スキルス胃癌 , 鑑別診断 pp.498-502
Published Date 2010/4/25
DOI https://doi.org/10.11477/mf.1403101888
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 Gastric syphilis, which has a predilection for involvement of the pyloric antrum, may resemble scirrhous carcinoma of the gastric antrum. The radiographic finding of gastric syphilis is characterized by a narrowed lumen of the entire antrum to the pylorus ring producing a funnel-shaped appearance. The endoscopic feature is multiple irregular and shallow erosions/ulcers with associated edema and hemorrhage in the antrum, the wall rigidity of which is not so severe. In addition, if multiple large verruciform lesions resembling syphilitic skin lesions are observed in the gastric body, they are valuable for the diagnosis of gastric syphilis.

 If the scirrhous carcinoma of the gastric antrum is suspected morphologically, bearing gastric syphilis in mind as one of the possible differential diagnoses, serologic tests should be carried out to test for syphilis.

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