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要旨●大腸鋸歯状病変は,過形成性ポリープ(HP),SSA/P,TSA,SSA/P with cytological dysplasiaの4者に大別されるが,本稿ではHP,SSA/P,TSAの内視鏡的特徴について概説した.HPとSSA/Pは一見類似した病変であるが,SSA/PはHPに比べて腫瘍径が大きく,局在が右側>左側結腸であり,粘液付着,開II型pit patternの割合が高かった.TSAは局在が左側>右側結腸であり,ほとんどが隆起型で,pit patternはIIIH型またはIVH型の割合が高く,TSAの診断はpit patternを用いることで容易であった.部分的に小隆起を認める場合や,雲状発育を呈したSSA/Pの一部が盛り上がっている場合は,同部でSM浸潤を来している可能性があり,拡大内視鏡観察を含めた詳細な診断が必要である.
Serrated lesions in the colorectum are classified into HP(hyperplastic polyp), SSA/P(sessile serrated adenoma/polyp), TSA(traditional serrated adenoma), and SSA/P with cytological dysplasia. In this report, we reviewed the endoscopic findings of HP, SSA/P, and TSA. We found that the characteristics of HP were similar to those of SSA/P ; however, SSA/P showed larger size, more frequent localization in the proximal colon, more mucin secretion on the lesion surface, and higher prevalence of open type pit pattern than did HP. In contrast, most TSAs showed localization in the distal colon, protruded appearance, and IIIH or IVH pit patterns. It is important to conduct a detailed observation using magnifying endoscopy for a local protruded area in SSA/P, because such areas have a potential for deep submucosal invasion.
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