Definition and Subclassification of LST in Relation to Clinical Significance Nana Hayashi 1 , Shinji Tanaka 1 , Kenjiro Shigita 2 , Yuki Ninomiya 2 , Yuzuru Tamaru 2 , Naoki Asayama 2 , Shiro Oka 1 , Kazuaki Chayama 2 1Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan 2Department of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan Keyword: LST , laterally spreading tumor , 側方発育型腫瘍 , 大腸癌取扱い規約 pp.1665-1672
Published Date 2014/11/25
DOI https://doi.org/10.11477/mf.1403200045
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 The term LST(lateral spreading tumor)was originally proposed by Kudo to describe colorectal tumors laterally spreading to more than 10mm in diameter. The term LST is now commonly used worldwide. However, the term LST had not been described in the General Rules for Clinical and Pathological Studies on Cancer of the Colon, Rectum and Anus(edited by the Japanese Society for Cancer of the Colon and Rectum). The definition and concrete colonoscopic images of LST have now been included in the 8th edition of the revised version, published in July 2013. The term LST is not used for macroscopic carcinoma but is a subclassification similar to superficial spreading tumor for esophageal and gastric carcinoma. In this report, we explain the history and clinical significance of LST subclassification, including the relationship with each clinicopathological feature.

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