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Granulomatous Gastritis Caused by Mycobacterium Infection, Report of a Case Ema Washio 1 , Motohiro Esaki 1 , Junji Umeno 1 , Kouichi Asano 1 , Naoya Kubokura 2 , Tomohiko Moriyama 1 , Yoshiteru Kumagae 3 , Risa Hida 3 , Minako Hirahashi 3 , Eiji Harada 4 , Takanari Kitazono 1 , Takayuki Matsumoto 5 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Department of Gastroenterology, Kimura Hospital, Fukuoka, Japan 3Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 4Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 5Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan Keyword: 肉芽腫性胃炎 , 抗酸菌 , 結核 , 抗結核療法 , 類上皮細胞肉芽腫 pp.1479-1486
Published Date 2016/10/25
DOI https://doi.org/10.11477/mf.1403200753

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 A 49-year-old woman was admitted to a referring hospital with symptoms of epigastric pain and nausea. Upper gastrointestinal endoscopy revealed multiple gastric ulcers and scars on the lesser curvature of the gastric body. Biopsies obtained from the ulcers and atrophic mucosa showed epithelioid cell granulomas with multinucleated giant cells. A skin test for tuberculosis with a purified protein derivative of tuberculin and QFT(QuantiFERON)was positive. CT(Computed tomography)demonstrated abdominal calcification and ground-glass opacity in the anterior basal segment of the right lung. Because cultures of gastric mucosa detected acid-fast bacilli twice, the patient was started on antituberculosis therapy. After 4 months, the therapy had to be stopped because of adverse effects. Repeated upper gastrointestinal endoscopy after the therapy showed scarred ulcers and negative results for mycobacterium culture. The diagnosis of granulomatous gastritis caused by mycobacterium infection was made.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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