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Surveillance Colonoscopy for Early Detection of Ulcerative Colitis-associated Colorectal Cancer Junko Kishikawa 1 , Shinsuke Kazama 1 , Keisuke Hata 1 , Hiroyuki Anzai 1 , Tsuyoshi Ozawa 1 , Hironori Yamaguchi 1 , Soichiro Ishihara 1 , Eiji Sunami 1 , Joji Kitayama 1 , Toshiaki Watanabe 1 1Department of Surgical Oncology, The University of Tokyo, Tokyo Keyword: 潰瘍性大腸炎 , colitic cancer , サーベイランス内視鏡 , 狙撃生検 pp.1479-1486
Published Date 2014/9/25
DOI https://doi.org/10.11477/mf.1403114271
  • Abstract
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 Patients with long-standing UC(ulcerative colitis)have an increased risk of colorectal cancer and are therefore recommended surveillance colonoscopy. To date, random biopsies have been performed during surveillance colonoscopy. This is because detection of UC-associated colorectal cancer is considerably difficult due to its atypical appearance and inflammation of background mucosa. However, recent improvements in endoscopic examination have enabled the endoscopic detection of UC-associated colorectal cancer. Consequently, it is now possible to perform target biopsies from endoscopically detected lesions, which is more effective than performing random biopsies. A randomized control study to compare random and target biopsies is currently underway in Japan.


Copyright © 2014, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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