Japanese

Problems of Helicobacter pylori-Negative Gastric Cancers in Gastric Cancer Screening Based on ABC Classification Kazuhiko Inoue 1 , Tomoari Kamada 2 , Noriaki Manabe 3 , Naohito Yamashita 1 , Hiroaki Kusunoki 1 , Keisuke Honda 1 , Jiro Hata 3 , Yoshinori Kushiyama 4 , Yasushi Uchida 4 , Ken Haruma 2 1Department of General Medicine, Kawasaki Medical School, Kurashiki, Japan 2Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan 3Department of Ultrasound and Endoscopy, Kawasaki Medical School, Kurashiki, Japan 4Gastroenterology of Matsue Red Cross Hospital, Matsue, Japan Keyword: Helicobacter pylori未感染胃癌 , ABC分類 , ペプシノゲン , 胃癌検診 pp.881-887
Published Date 2014/5/25
DOI https://doi.org/10.11477/mf.1403114177
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 The risk for gastric cancer can be diagnosed by the ABC classification method, comprising a combination of serum levels of Helicobacter pylori(H. pylori)antibody and PG (pepsinogen) method. Group A, with H. pylori antibody(-)and PG method(-), is considered a super-low risk group. After we classified 582 gastric cancer cases using the ABC classification, 56 cases(9.6%)fell into Group A, 109 cases(18.7%)in Group B-1, 77 cases(13.2%)in Group B-2, 309 cases(53.1%)in Group C, and 31 cases(5.3%)in Group D. A significant number of gastric cancers was classified as Group A. In Group A, more cases were of H. pylori-infected gastric cancers than H. pylori uninfected gastric cancers. Therefore, we must develop a method for separating Group A cases into those with H. pylori infection in the past and those with H. pylori infection at present.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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