Helicobacter pyloriと胃癌―背景胃粘膜の立場から―いわゆる鳥肌胃炎

Nodular Gastritis and Gastric Cancer

要旨　鳥肌胃炎の内視鏡的所見の特徴として小結節状隆起が前庭部から胃角部を中心にほぼ均等に分布し，隆起の中心に陥凹した白色斑点が認められた．また，鳥肌胃炎に合併した胃癌の特徴はH. pylori陽性の胃体部に発生する未分化型胃癌であった．鳥肌胃炎を診断した際には，胃体部を特に注意深く内視鏡観察することが重要であり，胃癌予防のためには早期の除菌治療が望ましいと考えられた．

　The endoscopic findings of nodular gastritis were mainly characterized by a unique, small granulated pattern in the antrum and angulus, and slightly depressed white spots were observed in the center of each nodularity. The cases of gastric cancer with nodular gastritis showed the same characteristics : all were diagnosed histologically as the diffuse-type and were located in the corpus with H. pylori infection. We recommend that in patients with nodular gastritis, endoscopists should carefully examine not only the antrum but also the corpus, and H. pylori should be eradicated as soon as possible to prevent gastric cancer in patients with nodular gastritis.