Endoscopic Diagnosis of Malignant Lesions of the Duodenum Tadashi Yokoyama 1 , Daizo Saito 1 , Tsutomu Ishikawa 2 , Atsushi Ochiai 3 , Shigeaki Yoshida 4 1Department of Internal Medicine, National Cancer Center Central Hospital 2Department of Radiological Dignosis, National Cancer Center Central Hospital 3Department of Pathology, National Cancer Center Research Institute 4Department of Internal Medicine, National Cancer East Hospital Keyword: 十二指腸癌 , 十二指腸腺腫 , 十二指腸悪性腫瘍 , 内視鏡診断 pp.641-649
Published Date 1993/6/25
DOI https://doi.org/10.11477/mf.1403106187
  • Abstract
  • Look Inside
  • Cited by

 We experienced 128 cases of duodenal malignant lesions during the period between 1971 and 1991. In 56 cases of secondary duodenal malignant lesions such as direct invasion of pancreatic carcinoma, differentiation between benign and malignant lesions was quite easy. There were 10 cases of primary duodenal carcinoma except for carcinoma of the ampulla of Vater. In 8 advanted cases, direct invasion of pancreatic cancer needed to be excluded. One early cancer of a small, 7×3 mm in size, polypoid lesion was found endoscopically in the bulb. The other early cancers were intramucosal carcinomas associated with adenoma. We also had 17 cases of pathologically-proved duodenal adenoma. A lesion in a patient with familial polyposis coli had grow from a small whitish spot to a large protrusion, a third of the circumference in size, in 4 years and 8 months, but no malignant change was detected in the resected specimen. It was almost impossible to distinguish a small carcinoid from a benign elevated lesion in the duodenom, and biopsy was considered to be the only method to detect such a small malignant lesion.

Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院