Duodenal Tumour and Tumour: like Lesion, a Review of Literatures Atsuro Morozumi 1 , Masayuki Fujino 1 1The FIrst Department of Internal Medicine, Yamanashi Medical College Keyword: 十二指腸腫蕩 , 分類 , 頻度 , 十二指腸癌 , カルチノイド腫瘍 pp.621-626
Published Date 1993/6/25
DOI https://doi.org/10.11477/mf.1403106184
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 Duodenal tumour and tumour-like lesion (duodenal tumours, for brevity) are relatively rare. Although radiological and endoscopic examinations have become popular and the duodenum is the segment next to the stomach, we are not so familiar with the duodenal tumours as those of the oesophagus, stomach and colon. Duodenal tumours may be devided in the following 3 categories: Classical symptomatic tumours, small asymptomatic lesions found by examinations, and endocrine cell tumours identified by immunohistochemical studies.

 With this classification, we discussed the general issues including the incidence. When the small intestine is viewed as a whole, small intestinal tumours are uncommon, in which non-epithelial tumours are predominant; compared to Europe, carcinoid tumours are less frequent in Japan. In duodenal carcinoma, those proximal to the duodenal papilla, particularly early carcinoma, are increasing, following the diffusion of radiological examination and endoscopy; early carcinoma is more frequent in the duodenal bulb than in the descending part.

 Furthermore, we discussed the reasons for low incidence of duodenal tumours, histogenesis of duodenal carcinoma, how to deal with carcinoma of the duodenal papilla and carcinoid tumour of the duodenum.

 Low incidence of duodenal tumours seems to be related to anatomical, physiological and immunological factors involving the small intestine and to the development and differentiation of the small intestine.

 Regarding carcinoid tumour, the concept of endocrine cell tumour should first be recognized. Similar to other small lesions including early carcinoma, careful endoscopy and more frequent use of immunohistochemistry will lead to new findings.

Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.


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