Early Gastric Cancer Associated with Solitary Submucosal Heterotopic Gastric Glands, Report of a Case Tadayuki Hara 1 , Hiroki Hasui 1 , Masato Moriguchi 1 , Yositeru Kaji 1 , Yoshito Yosikawa 2 1Department of Internal Medicine, Takamatsu Heiwa Hospital 2Department of Surgery, Takamatsu Heiwa Hospital Keyword: 孤立性胃粘膜下異所腺 , 前癌病変 , 早期胃癌 pp.1089-1093
Published Date 1994/9/25
DOI https://doi.org/10.11477/mf.1403105920
  • Abstract
  • Look Inside
  • Cited by

 A 48-year-old man who had diabetes mellitus was admitted to our hospital because of epigastralgia. Endoscopic examination with biopsy revealed an early gastric cancer of type Ⅱa+Ⅱc lesion on the greater curvature of the body. Microscopical examination disclosed moderately differentiated tubular adenocarcinoma and a proximal gastrectomy was therefore performed.

 Histological findings showed that early gastric carcinoma was localized in the fundic gland area without intestinal metaplasia, and the heterotopic gastric glands with no evidence of cytologic or histologic malignancy were able to be seen at the peripheral lesion of the submucosal layer. A contact point was revealed between the neoplastic cells and the non-neoplastic cells in the heterotopic gastric glands. No submucosal heterotopic gastric glands other than the present lesion were observed in the stomach. Therefore, we concluded that a solitary submucosal heterotopia of the stomach could be considered to have a specific relationship to gastric carcinogenesis.

Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院