Differentiated Carcinoma in the Fundic Gland Area, Report of a Case Kenshi yao 1,2 1Department of Gastroenterology Fukuoka University Chikushi Hospital Keyword: 体部腺領域 , 分化型癌 , 腺窩上皮型癌 , 粘液染色 pp.1083-1088
Published Date 1994/9/25
DOI https://doi.org/10.11477/mf.1403105919
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 Through endoscopic follow-up study of gastric hyperplastic polyp, a 70-year-old woman was diagnosed as having early gastric cancer, type Ⅱa+Ⅱc. Radiologically, the flat elevated lesion 30 mm in diameter with irregular depressed area was identified at the anterior wall along the greater curvature in the upper portion of the gastric body. In addition to his, some aggregated flat and granular lesions were seen at the edge of the tumor. Distal gastrectomy was performed. By histopathological examination, the tumor was shown to be a well differentiated carcinoma invading the deeper portion of the submucosal layer, and the background epithelium showed fundic-type mucosa without intestinal metaplasia. The aggregated flat and granular lesions were composed of extremely differentiated carcinoma resembling gastric foveolar epithelium. The mucosubst ance histochemistry of the carcinoma revealed Alcian blue (AB)(-), periodic acid Schiff (PAS)(+), galactose oxidase Schiff (GOS)(+) and paradoxical concanavalin A (Con A Ⅲ)(-). These results suggested that the tumor originated from the foveolar epithelium and could be classified as "foveolar type carcinoma".

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