Japanese

Clinicopathological Study of Gastric Carcinoma in the Fundic Glandular Mucous Membrane Area Yasumasa Baba 1 , Tomohisa Saiki 1 , Hiroyuki Sakata 1 1Department of Internal Medicine, Cancer Institute Hospital Keyword: 胃底腺粘膜 , 癌組織型 , 分化型癌 , 粘液組織染色 pp.1031-1038
Published Date 1994/9/25
DOI https://doi.org/10.11477/mf.1403105910
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 We studied the relationship between background gastric mucous membrane and histologic types of carcinoma in 907 patients having gastric carcinomas excised in the Department of Surgery (Cancer Institute Hospital) and pathologically examined between 1988 and 1993. In the pyloric glandular mucous membrane area (including the cardiac glandular mucous membrane area), well-differentiated carcinomas were found in 50% of the cases (313/624) while undifferentiated carcinoma were found, at an equal rate, in 50% of the cases (311/624). In the intermediate mucous membrane area, well-differentiated carcinomas were found in 32% of the cases (58/180) while undifferentiated carcinomas were found in 68% of the cases (122/180). In the gastric fundic glandular mucous membrane area, well differentiated carcinomas were found in 2% of the cases (2/103) while undifferentiated carcinomas were found in 98% of the cases (101/103), showing that most carcinomas were undifferentiated. Macroscopically, the two cases of well-differentiated carcinomas in the gastric fundic glandular mucous membrane area were the depressed type. In one case the cancer had invaded the muscular propria (mp), and, in the other case, the cancer was limited to the submucosal layer (sm). In neither case was there metastasis to the lymph nodes. In these well-differentiated carcinomas in the gastric fundic glandular mucous membrane area, the mucous was histochemically stained and the carcinomas in each case possessed the form and properties of intestinal types. Therefore, it was suspected that the carcinomas had generated from a local intestinal metaplasia lesion in the gastric fundic glandular mucous membrane.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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