粘膜下腫瘍様の形態を呈した胃底腺領域の分化型癌の1例

Gastric Carcinoma of Differentiated-type Arising from the Fundic Gland Mucosa, Report of a Case

要旨　患者は45歳，女性．胃集団検診で胃の異常所見を指摘，内視鏡検査で胃体部の粘膜下腫瘍と診断された．2年後の内視鏡検査では粘膜下腫瘍の形態はとるものの，大きさは増し，中央に陥凹を有するようにもなった．病理組織学的には分化型癌であり，深達度はmであった．また，背景粘膜は胃底腺粘膜であり腸上皮化生は認めなかった．

　A 45-year-old woman who had an abnormality pointed out by gastric mass survey in May 1985, came to our center. Gastrofiberscopy led to the diagnosis of submucosal tumor in the greater curvature of the middle corpus. Follow-up study was done in July, 1987. The size of the tumor had enlarged and the ulceration appeared at its surface. So, malignant tumor was highly suspected and biopsy was carried out at that time. That specimen showed tubular adenocarcinoma. Gastrectomy was carried out. By the histopathological study, the carcinoma was shown to be a differentiated-type of early carcinoma arising from the fundic gland mucosa. Its invation was limited to the mucosa.