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Intraepithelial Carcinoma Mimicking Subepithelial Type (0-lsep), Report of a Case Masaki Nakamura 1 , Tomoko Ishibashi 1 , Hitoshi Umezu 1 , Toshikazu Yamaguchi 1 , Toshiaki Ohba 1 1Department of Internal, Medicine, Yoyogi Hospital Keyword: 食道上皮内癌 , 食道早期癌の深達度診断 pp.852-856
Published Date 1994/7/25
DOI https://doi.org/10.11477/mf.1403105863
  • Abstract
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 A 58-year-old woman without symptoms underwent upper gastrointestinal endoscopic examination as a routine check-up. It disclosed a polypoid lesion which had gentle marginal slope and was 2~3mm high in the mid-thoracic esophagus (about29~32cm from the incisors). Contraction rings of the esophagus in the vicinity of the polypoid lesion disappeared by pneumatic withdrawal. The second examination was preformed by an oblique-viewing endoscope, the proximal side of the lesion had more gentle marginal slope and was lower than the distal side. There were two longitudinal white-coated erosions on the proximal portion of the lesion, and erythematous area on the distal part. The white coated and erythematous areas were negative for Lugol staining. Radiographic examination with double contrast method showed the lesion as a small granular area which had the same length as a vertebra in the mid-thoracic esophagus. No wall stiffness (poor distensibility) nor irregularity was noted on a profile view of the lesion. Histologic examination of the surgically resected specimen disclosed that the lesion, 19×7mm in size, was well differentiated squamous cell carcinoma limited to the mucosal membrane (invasive depth: ep) which had the thickness of 0.1~0.15mm (macroscopic type: 0-Ⅱa). There were loose fibrosis and lymphoid follicles formation with an enlarged germinal center in the lamina propria mucosae. In addition, dilated blood vessels with hemorrhage were seen in the submucosa beneath the lesion.


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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