Poorly Differentiated Squamous Cell Carcinoma of the Esophagus with Lymphoid Stroma Seeming to be Type 0-Isep, Report of a Case Osamu Chino 1 , Hiroyasu Makuuchi 1 , Hideo Shimada 1 , Takayuki Nishi 1 , Hikaru Tanaka 1 1Department of Surgery, School of Medicine, Tokai University Keyword: 食道表在癌 , 0-Isep型 , 粘膜下腫瘍様形態 , lymphoid stroma pp.227-232
Published Date 2000/2/25
DOI https://doi.org/10.11477/mf.1403104655
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 An esophageal lesion was detected in a 67-year-old man by endoscopy at a nearby hospital, when he visited there complaining of upper abdominal discomfort. No malignant features were noted in the biopsy specimen taken from the esophageal lesion on the left-posterior wall of the lower thoracic portion. He was admitted to the Tokai University hospital for further clinical examination and treatment. The endoscopic findings revealed that the lesion was protruding with a central slight depression, covered by non-epithelial esophageal epithelium, mimicking a submucosal tumor, and stained with iodine. The biopsy specimen showed atypical squamous cells. Under the diagnosis of type 0-Isep, superficial esophageal carcinoma, endoscoipc mucosal resection was performed at the patient's request. The histopathological findings of the resected specimen led to the diagnosis of poorly differentiated squamous cell carcinoma with marked lymphoid stroma and overlying non-epithelial squamoua epithelium. The depth of invasion was sm2, infγ, ly0, v0. A subtotal esophagectomy using a right thoraco-laparotomy with lymph node dissection, D3, was performed because of suspicion of lymph node metastasis. Metastasis of lymph nodes #3, 7 was positive for cancer cells.

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