予後からみた多発胃癌

Study of Multiple Gastric Cancer

要旨　多発胃癌310例(切除胃癌の8.8％)，685病巣について単発癌3,205例(3,205病巣)と比較した．多発胃癌病巣は単発胃癌に比べてC領域にある割合が高く，隆起型，平坦型が高率で，分化型が大部分であった．残胃の癌の検討から，多発癌として同じ傾向を有するものがあると考えられた．多発癌はリンパ節転移率が低い(33.3％；単発43.8％)ものの生存率は単発癌と同じであった(5年生存率：73.5％，70.0％，10年生存率：59.1％，57.2％)．今後，多発癌の取り扱いについての基準が必要であろう．

　Three hundred and ten patients with multiple gastric cancer (MUL, 685 lesions) were compared to 3,205 patients with single lesion (SIN) in terms of histopathological characteristics, lymph node metastasis and survival rate. The following items were significantly more common in MUL than in SIN (p＜0.05): location of the upper third area, elevated and flat types, and well differentiated type. The survival rate of MUL was almost equal to that of SIN, while the incidence of lymph node metastasis of MUL was lower than that of SIN.

　These results suggest that a new histopathological and clinical classification is necessary for MUL in the future since MUL has a different biological behavior from SIN.