Endoscopic and Radiologic Diagnosis of Neoplastic Lesions in Patients with Ulcerative Colitis Takayuki Matsumoto 1 , Mitsuo Iida 2 1The Second Department of Internal Medicine, Faculty of Medicine, Kyushu University 2Division of Gastroenterology, Department of Medicine, Kawasaki Medical School Keyword: 潰瘍性大腸炎 , 大腸癌 , dysplasia , 大腸内視鏡検査 , 注腸X線検査 pp.613-628
Published Date 1995/4/25
DOI https://doi.org/10.11477/mf.1403105398
  • Abstract
  • Look Inside
  • Cited by

 The endoscopic and radiographic features of cancer and dysplasia in patients with long-standing ulcerative colitis were investigated. Among 121 biopsy specimens obtained during surveillance colonoscopy in nine patients, 20 were diagnosed as dysplasia or cancer. Seventeen of these 20 specimens were obtained either from granular mucosa or from nodular elevations. In another investigation, 20 lesions with the established diagnosis of dysplasia or cancer were endoscopically and/or radiographically recognized as either nodular elevations (11 lesions), granular mucosa (six lesions), elevations accompanied by granular mucosa (two lesions), or a depression surrounded by granular mucosa (one lesion). However, we failed to identify one cancer preoperatively. The radiographic features of the granular mucosa were characterized by minute protrusions accompanied by irregular contours. These findings suggest that dysplasia or cancer in ulcerative colitis can be recognized under colonoscopy, and that radiographs may become available for cancer surveillance programs for this disease.

Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院