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Endoscopic Findings in Ulcerative Colitis Using Narrow-band Imaging Keisuke Kawasaki 1 , Motohiro Esaki 2,3 , Koichi Kurahara 4 , Yoichiro Nuki 3 , Makoto Eizuka 5 , Yumi Oshiro 6 , Minako Fujiwara 7 , Shunichi Yanai 1 , Yosuke Toya 1 , Yasuko Fujita 5 , Noriyuki Uesugi 5 , Kazuyuki Ishida 5 , Shotaro Nakamura 1 , Tamotsu Sugai 5 , Takayuki Matsumoto 1 1Division of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan 2Department of Endoscopic Diagnostics and Therapeutics, Saga University Hospital, Saga, Japan 3Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 4Division of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan 5Department of Diagnostic Pathology, Iwate Medical University, Morioka, Japan 6Department of Pathology, Matsuyama Red Cross Hospital, Matsuyama, Japan 7Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Keyword: 潰瘍性大腸炎 , NBI , 潰瘍性大腸炎関連腫瘍 pp.67-75
Published Date 2019/1/25
DOI https://doi.org/10.11477/mf.1403201562

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  • Abstract
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 Objective:The aim of this investigation was to clarify the endoscopic features in UC(ulcerative colitis)using NBI(narrow-band imaging).

 Methods:We identified 73 segments of remission-phase UC and 13 UCAN(UC-associated neoplasia)at our institution, followed by retrospective investigation of the colonoscopy findings.

 Results:In an inactive mucosa, the MVP(mucosal vascular pattern)under non-magnifying NBI endoscopy could be divided into superficial vessels, black vessels, and lacking superficial vessels. When coupled with magnifying endoscopy, MVP could be classified into honeycomb-like vessels and irregular vessels. Inflammatory cell infiltrates and crypt distortion were more frequently observed in the segments with an obscure MVP than in those with a clear MVP. Moreover, among the 13 UCAN, all invasive cancers were observed to be of type 2B or type 3 as per the Japan NBI Expert Team classification and to be of type VI or type VN as per the pit pattern classification.

 Conclusions:NBI and magnifying endoscopy may be invaluable for the diagnosis of the grade of inflammation in remission-phase UC or invasion depth in UCAN.


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