Colorectal Cancer in Patients with Inflammatory Bowel Disease in Japan Takashi Hirai 1 , Tomoyuki Kato 1 , Yukihide Kanemitu 1 1Department of Gastroenterological Surgery, Aichi Cancer Center Hospital Keyword: 炎症性腸疾患 , 大腸癌 , 潰瘍性大腸炎 , Crohn病 pp.887-893
Published Date 2002/6/25
DOI https://doi.org/10.11477/mf.1403104484
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 A questionnaire related to the 55th meeting of the Japanese Society for Cancer of the Colon and Rectum was sent to members of the Society. It concerned colorectal cancer complicated with inflammatory bowel disease. One hundred and twenty-three patients with colorectal cancer were diagnosed during follow-up of 4,796 patients with ulcerative colitis. The incidence rate of colorectal cancer was less than 2% in the just 10 years of follow-up, about 5% after 10 years, and more than 10% after 21 years of follow-up. Early cancer made up 42% of all patients, and a 5 year survival was enjoyed by 87% of patients with curability A.

 On the other hand, twelve patients with colorectal cancer were diagnosed during follow-up of 2,500 patients with Crohn's disease. The incidence of colorectal cancer didn't increase relative to the follow-up time. Most of the cancers affected the rectum and anus, and advanced locally, so the oncological outcome was poor.

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