The Present Situation of Colorectal Cancer Associated with Ulcerative Colitis in the West & Japan Osamu Tsuruta 1,2 , Hiroshi Kawano 1,2 , Yuichiro Tsuji 1,2 , Takeshi Toubaru 1,2 , Atsushi Toyonaga 1,2 1Department of Medicine Ⅱ, Division of Gastroenterology and Endoscopy, Kurume University School of Medicine Keyword: ulcerative colitis(潰瘍性大腸炎) , colorectal cancer(大腸癌) , colitic cancer , dysplasia , surveillance colonoscopy pp.895-902
Published Date 2002/6/25
DOI https://doi.org/10.11477/mf.1403104486
  • Abstract
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 Patients with long-term ulcerative colitis (UC) have an increased risk for colorectal cancer. Dysplasia is believed to be a precursor lesion in the pathway toward the development of invasive cancer. As such, surveillance programs using colonoscopic biopsy specimens to detect dysplasia and early cancer have been implemented. However, these surveillance colonoscopies haven't provided satisfactory results in prognosis. It is desirable to detect not only DALM but also flat dysplasia to obtain a more favorable prognosis. We should devote attention to detecting faint red mucosa, disorder of surface structure and neoplastic pit pattern which phenomena are related to flat dysplasia.

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