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要旨 サイトメガロウイルス(CMV)感染は潰瘍性大腸炎の増悪因子の1つとして知られている.なかでも,重症例に多く,中毒性巨大結腸症や予後不良との関連が示唆されている.今回,組織学的および血清学的に評価しえた潰瘍性大腸炎患者14例において,大腸におけるCMV感染,臨床像および大腸X線・内視鏡所見を検討した.その結果,CMV感染を認めた潰瘍性大腸炎4症例では,打ち抜き様潰瘍,地図状潰瘍および縦走潰瘍・びらんを比較的高率に認めた.
Cytomegalovirus (CMV) infection has been recognized as an exacerbating factor for ulcerative colitis. This infection is possibly related to severe disease, toxic megacolon, and poor prognosis. In this study, we included 14 patients with ulcerative colitis who were evaluated histologically and serologically, and we reviewed the presence of CMV infection, clinical features, radiographic and colonoscopic findings. Four CMV-infected patients with ulcerative colitis frequently presented with punched-out ulcers, geographic ulcers, and longitudinal orientation of ulcers.
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