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Extension of Atrophic Gastritis in Patients with and without Helicobacter pylori Infection Kiichi Satoh 1 , Ken Kihira 1 , Ken Kimura 1 1Department of Gastroenterology, Jichi Medical School Keyword: Helicobaeter pylori , 萎縮性胃炎 , 萎縮性胃炎の拡大 , 内視鏡的萎縮境界 pp.1131-1136
Published Date 1998/7/25
DOI https://doi.org/10.11477/mf.1403103773
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 Helicobacter pylori is considered a causative factor in the development and extension of atrophic gastritis, because most patients with atrophic gastritis are infected with H. pylori. Our cross-sectional study showed that the prevalence of H. pylori infection was significantly higher in patients with a moderate extent of atrophic gastritis (extending to the lesser curvature of the body) (97%, 33/34) than in those with non-atrophic (32%, 6/19) and antral atrophic gastritis (64%, 7/11). A four-year follow-up study of Sakaki et al. (Gastroenterol Endosc 38: 1587-1589, 1996) showed that the extension of atrophic gastritis was found in 31% of H. pylori-positive patients, but in none of those without H. pylori infection. Assuming that the acquisition of H. pylori infection occurs in childhood (less than five years of age), these studies suggest that atrophic gastritis extends to the lesser curvature of the body about 30 years after its acquisition. The time and speed of the extension of atrophic gastritis are different in each patient, and some factors other than H. pylori infection may also be involved in the extension.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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