Endoscopic and Histological Issues in Diagnosing Gastric Carcinoma Shinya Abe 1 , Akimichi Chonan 2 , Takayuki Masuda 3 , Tetsuya Noguchi 1 , Daisuke Shibuya 1 1Cancer Detection Center of Miyagi Cancer Society 2Department of Gastroenterology, JR Sendai Hospital 3Department of Medical Technology, College of Medical Sciences, Tohoku University Keyword: 胃癌 , 内視鏡診断 , 生検診断 pp.1477-1484
Published Date 1999/11/25
DOI https://doi.org/10.11477/mf.1403102862
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 We examined the endoscopic and histological diagnosis of gastric lesions. Biopsies were carried out in 32.8% of all the endoscopic examinations made of the upper gastrointestinal tract. It was shown that the endoscopic diagnoses were sensitive in 84.66% of the cases and specifically correct in 99.10% of the cases. False 15.34% of the cases were falsely diagnosed as negative. The causes of the false negative endoscopic diagnoses were the impossibility of or the great difficulty of endoscopic diagnosis of the lesion. Twenty patients were falsely diagnosed as positive. Seven of these were cases of the acute stage or recurrence of ulcerative lesions. Sensitivity and specificity of the histological diagnosis by biopsy specimens were 96.16% and 99.98% respectively. 3.84% of the patients with carcinoma were falsely diagnosed as negative by histological diagnosis. The causes of the false negative histological diagnoses by biopsy specimens were difficulty in histological diagnosis and character of the carcinoma and impossibility of endoscopic diagnosis.

 In order to decrease false negative diagnoses by biopsy specimens, it is important to diagnose the lesion correctly endoscopically and perform the biopsy exactly.

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