The State of the Art and Problems of Endoscopic Biopsy in Diagnosis of Gastric Cancer Takashi Yao 1 , Osamu Miura 2 , Toyokazu Kawano 2 1Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University 2The Institute of Gastroenterology of Hofu Keyword: 胃癌 , 胃生検 , Group分類 pp.1469-1475
Published Date 1999/11/25
DOI https://doi.org/10.11477/mf.1403102860
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 The endoscopic appearances of cases, in which endoscopic biopsy was performed, were classified into five groups,G1; definitely benign,G2; probable benign,G3; neoplasm of borderline malignancy (adenoma),G4; suspicious of malignancy,G5; definitely malignant. Then, the correlation between the endoscopic diagnosis and histologic diagnosis was evaluated.

 Of 737 cases, 413 were classified into G1, 256 were classified into G2, 18 were classified into G3, 21 were classified into G4, and 29 were classified into G5. The incidences of malignancy in G1, 2, 3, 4 and 5 were 0.2%, 1.6%, 11.1%, 66.7% and 100%, respectively. The endoscopic diagnosis was in good agreement with the histologic diagnosis. Its ratio of agreement was 95.8%. Of 737 cases, histology was unable to detect malignancy in only 0.9%of G4 or G5 cases, whereas 0.7% of G1 or G2 cases revealed malignancy.

 Malignancy could be correctly distinguished from benignancy by endoscopic appearance in almost all cases. However, biopsy was performed in most benign cases, because malignancy with benign appearance does exist, and histologic diagnosis by biopsy is considered to be essential for a final diagnosis.

Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.


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