Verification of the Usefulness of Magnifying Endoscopy with Narrow Band Imaging for Diagnosing Early Gastric Carcinoma from a Pathological Viewpoint Ken Nishikura 1 , Masaaki Kobayashi 2 , Kazuyoshi Yagi 3 , Yoichi Ajioka 4 1Division of Molecular and Functional Pathology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan 2Department of Endoscopy, Niigata University Medical and Dental Hospital, Niigata, Japan 3Department of Internal Medicine, Niigata Prefectural Yoshida Hospital, Tsubame, Japan 4Division of Molecular and Diagnostic Pathology, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan Keyword: 拡大内視鏡 , NBI , 早期胃癌 , 病理組織診断 , 形質 pp.825-840
Published Date 2011/5/25
DOI https://doi.org/10.11477/mf.1403102249
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 The aim of this study was to verify the usefulness ME-NBI(magnifying endoscopy with narrow band imaging)for diagnosing early gastric carcinoma. Formalin-fixed and paraffin-embeded materials were histopathologically evaluated according to Yagi-Kobayashi's classfication of ME-NBI. All lesions of type-A group(100%,15/15)demonstated gastric-dominant phenotype. All lesions of type-B group(100%,6/6)showed intestinal-dominant phenotype. On the other hand, there was a higher frequency of moderately to poorly differentiated carcinoma(84.2%,16/19)and gastrointestinal phenotype ones(52.6%,10/19)in the type-C group.

 The ME-NBI seemed to be useful for diagnosing early gastric carcinoma, but there were some difficult and misleading cases with special histopathological findings such as moderately differentiated carcinoma covered with non-neoplastic epithelium on their surface, which urges us to be careful in diagnosing early gastric carcinomas with ME-NBI.

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