Limitations of Magnifying Endoscopy(ME)for Determining the Margins of Lateral Extent of Early Gastric Cancer Kenshi Yao 1 , Takashi Nagahama 2 , Hiroshi Tanabe 3 , Shinichiro Maki 2 , Kozue Tsurumi 2 , Yoichiro Ono 2 , Motochika Yasaka 2 , Toshiyuki Matsui 2 , Akinori Iwashita 3 1Department of Endoscopy, Fukuoka University Chikushi Hospital, Chikushino, Japan 2Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan 3Department of Pathology, Fukuoka University Chikushi Hospital, Chikushino, Japan Keyword: 拡大内視鏡 , 早期胃癌 , 狭帯域光観察 , narrow band imaging , NBI pp.903-914
Published Date 2011/5/25
DOI https://doi.org/10.11477/mf.1403102256
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 Aims : ME(magnifying endoscopy)may allow reliable delineation of the lateral extent of gastric carcinoma prior to endoscopic submucosal dissection method. However, we sometimes encounter difficult lesions whose margins cannot be determined by ME. The aim of this study was to investigate the prevalence of these difficult lesions and to clarify their clinicopathological characters of such lesions.

 Methods : We investigated 446 early gastric cancers, of the difficult lesions which had been resected by ESD. We reviewed all the images and the records of these cases, and these numbers were identified. Furthermore, we investigated the histopathological findings characteristic for these difficult lesions.

 Results. The prevalence of the difficult lesions was 4%(18/446).The histopathological characters of these lesions were undifferentiated carcinoma, and differentiated carcinoma with very-well differentiation or with moderate differentiation.

 Conclusions : Instead of performing ME, we need to take multiple biopsies from the surrounding mucosa according to standard endoscopic findings especially in case of undifferentiated carcinoma.

Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.


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