A Comparative Enteroscopic Study of Nonsteroidal Anti-inflammatory Drug-induced Enteropathy and Chronic Nonspecific Ulcers of the Small Intestine Takayuki Matsumoto 1 , Motohiro Esaki 1 , Shinichiro Yada 1 , Tomohiko Moriyama 1 , Hideki Koga 1 , Shotaro Nakamura 1 , Fumihito Hirai 2 , Toshiyuki Matsui 2 , Mitsuo Iida 1 , Tsuneyoshi Yao 2,3 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan 3Sada Hospital, Fukuoka, Japan Keyword: 非特異性多発性小腸潰瘍症 , 非ステロイド性抗炎症薬 , カプセル内視鏡 , ダブルバルーン内視鏡 pp.951-959
Published Date 2009/5/25
DOI https://doi.org/10.11477/mf.1403101678
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 We compared enterosopic findings between 14 patients with nonsteroidal anti-inflammatory drug-induced enteropathy(NSAIDs-enteropathy)and 9 patients with chronic nonspecific multiple ulcers of the small intestine(CNSU). Single or multiple concentric sternosis was found in 29% of NSAIDs enteropathy and in 100% of CNSU. Non-stricturing circular ulcers were found in 50% of NSAIDs-enteropathy and in 67% of CNSU. Longitudinal or oblique ulcer was seen more frequently in CNSU(44%)than in NSAIDs-enteropathy(7%). In contrast, diminutive or aphthous ulcers were found more frequently in NSAIDs enteropathy(50%)than in CNSU(22%). These findings suggest that CNSU is characterized by intractable and large ulcers, while diminutive ulcers are characteristic of NSAIDs enteropathy.

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