5) NSAIDs起因性腸炎

NSAIDs-induced Small Bowel Injury

要旨　カプセル内視鏡およびダブルバルーン小腸内視鏡の導入により小腸病変の診断能が画期的に向上した．ことにnonsteroidal anti-inflamatory drugs（NSAIDs）による小腸病変に関しては膜様狭窄以外にもびらん，アフタ様潰瘍，打ち抜き状円形潰瘍などの病変が指摘されるようになった．またNSAIDsによる出血性の小腸潰瘍についてはダブルバルーン小腸内視鏡により止血できる場合もあり，診断および治療に関して大きな変革を迎えている．

　Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) may cause small intestinal injuries that could be associated with intestinal hemorrhage. Recent advances in wireless capsule endoscopy and double balloon enteroscopy (DBE) has enabled the diagnosis of small bowel lesions induced by NSAIDs. From the findings of DBE examination, aphthoid ulcer, discrete round ulcer, and circular ulcer with or without stricture are reported as NSAIDs-induced small bowel injuries. These findings add further understanding of the NSAIDs-induced small bowel injury.