Stomach and Intestine(Tokyo) Volume 42, Issue 11 (October 2007)
Japanese

Clinical Characteristics and Problems of Mixed(Involving Differentiated and Undifferentiated)Type Early Gastric Cancer―Pretreatment Assessment of Tumor Extension Yoji Takeuchi 1 , Noriya Uedo 1 , Hiroyasu Iishi 1 , Takashi Kizu 1 , Rika Miyoshi 1 , Takuya Inoue 1 , Motohiko Kato 1 , Eriko Masuda 1 , Koji Higashino 1 , Ryu Ishihara 1 , Masaharu Tatsuta 1 , Maoko Matsumura 2 , Shingo Ishiguro 2 1Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan 2Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan Keyword: 未分化型混在早期胃癌 , 拡大内視鏡 , 範囲診断 , 狭帯域フィルター内視鏡システム pp.1635-1645
Published Date 2007/10/25
DOI https://doi.org/10.11477/mf.1403101213
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 Background:Endoscopic submucosal dissection(ESD)allows the resection of larger lesions than in the past. According to expansion of the criteria for endoscopic treatment of early gastric cancer(EGC), the incidence of mixed(involving differentiated and undifferentiated)type EGC is increasing in the patients resected by ESD. We should know about the characteristics and problems in the pretreatment assessment of tumor extent in mixed type EGC.

 Objective:To investigate the efficacy of magnifying endoscopy with narrow band imaging(NBI)for pretreatment assessment of tumor extent for mixed type EGC.

 Materials:429 EGCs resected en bloc by ESD.

 Interventions:We compared the incidence of lateral margin positive resection in the non-magnifying endoscopy group and the magnifying endoscopy group. We also investigated characteristics and the usefulness of magnifying endoscopy for pretreatment assessment of tumor extent in mixed type EGC.

 Results:There was no significant difference between the two groups as regards incidence of lateral margin positive resection, because of allocation bias. Pretreatment assessment using magnifying endoscopy with NBI is efficacious for decreasing the incidence of lateral margin positive resection in EGC with unclear margin diagnosed by chromoendoscopy. Mixed type EGC was relatively larger than non-mixed type EGC, and was comprised mainly of depressed type cancers invading to the submucosal layer. Based on chromoendoscopy, mixed type EGC often had unclear margins. Magnifying endoscopy using NBI can decrease the incidence of lateral margin positive resection in mixed type EGC.

 Conclusion:Magnifying endoscopy with NBI used in pretreatment assessment of tumor extent for mixed type EGC can decrease the incidence of lateral margin resection.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

基本情報

05362180.42.11.jpg
胃と腸
42巻11号 (2007年10月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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