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Diagnosis of Differentiated-type SM1 Gastric Cancer Using a Narrow Band Imaging System with Magnifying Endoscopy Yoji Takeuchi 1 , Noriya Uedo 1 , Hiroyasu Iishi 1 , Motohiko Kato 1 , Eriko Masuda 1 , Sachiko Yamamoto 1 , Shunsuke Yamamoto 1 , Koji Higashino 1 , Ryu Ishihara 1 , Masaharu Tatsuta 1 , Shingo Ishiguro 2 1Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan 2Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan Keyword: 胃分化型癌 , 深達度診断 , 狭帯域フィルター内視鏡システム , 拡大内視鏡 pp.111-120
Published Date 2007/1/25
DOI https://doi.org/10.11477/mf.1403100390
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 Background : According to clinicopathological studies and improvement of endoscopic procedures (ex. endoscopic submucosal dissection ; ESD), early gastric cancers with minute invasion (<500μm) to the submucosal layer (SM1 gastric cnacer) have become candidates for endoscopic resection. To predict the depth of SM1 gastric cancer is important.

 Objective : To evaluate the efficacy of the narrow band imaging system with magnifying endoscopy (NBI-ME) for predicting the depth of differentiated-type early gastric cancer.

 Materials : A total of 94 patients with 98 early gastric cancers were enrolled in this retrospective study.

 Interventions : All of the tumors were observed and recorded using NBI-ME. We investigated the NBI-ME images, differentiation of the tumor and depth of the tumor invasion.

 Main outcome : Revelation of the prevalence of density change and destructive sign of gland pattern in the tumor.

 Results : The prevalence of density change revealed by the NBI-ME system was lower in intramucosal cancer (5) than in SM1 cancer (86%) and SM2 cancer (67%). The density change had a tendency to be lower in invading lesions. The prevalence of destructive sign was lower in intramucosal cancer (10%) and SM1 cancer (29%) than in SM2 cancer (92).

 Conclusion : The data suggested that minute invasion of the tumor reflects the NBI-ME findings. NBI-ME is efficacious to predict the depth of tumor invasion for selected patients with differentiated-type early gastric cancer.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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