Primary Mucosa-associated Lymphoid Tissue(MALT)Lymphoma of the Rectum Presenting as a Minute Submucosal Tumor-like Lesion, Report of a Case Tomohiko Mannami 1 , Keiko Fujiwara 1 , Yoshihiro Ohfuji 1 , Katsuhiro Enomura 1 , Wakako Oda 2 , Ichiro Yamadori 2 , Tadashi Yoshino 3 , Haruhiro Yamashita 1 1Department of Gastroenterology, National Hospital Organization Okayama Medical Center, Okayama, Japan 2Department of Pathology, National Hospital Organization Okayama Medical Center, Okayama, Japan 3Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan Keyword: MALTリンパ腫 , 直腸 , 内視鏡的粘膜切除術 , 内視鏡的粘膜下層剥離術 , PCR pp.1417-1425
Published Date 2007/8/25
DOI https://doi.org/10.11477/mf.1403101184
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 A 69-year-old Japanese female underwent colonoscopy for further examination of occult blood in the stool. A sessile polypoid lesion resembling a submucosal tumor 7~8 mm in diameter was found in the upper rectum. The elevation, appearing to be the same color as adjacent normal mucosa, had a smooth and even surface with telangiectasia. En bloc, complete resection was performed endoscopically. Histology revealed that the tumor was predominantly confined to the lamina propria mucosae and consisted of centrocyte-like cells that were shown by immunohistochemistry to be positive for B-cell markers. These findings were morphologically consistent with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type(MALT lymphoma). Polymerase chain reaction(PCR)demonstrated monoclonality of the lymphoma cells. No other site of involvement was identified by the staging work-up. There is no endoscopical or histological evidence of lymphoma in the rectum after 17 months of follow-up. A minute primary MALT lymphoma of the rectum has been rarely reported.

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