Endo-cytoscopy System for Upper Gastrointestinal Tract Yoichi Kumagai 1 , Shigeru Yamasaki 1 , Michio Iida 1 1Department of Surgery, Ohta General Hospital Foundation Ohta Nishinouchi Hospital, Kohriyama, Japan Keyword: endo-cytoscopy system , 超拡大観察 , virtual histology , 食道癌 , 胃癌 pp.884-890
Published Date 2007/4/26
DOI https://doi.org/10.11477/mf.1403101103
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 The endo-cytoscopy system consists of two flexible endoscopes whose magnifying capability is 450× and 1,125×. We can observe the cells existing on the mucosal surface at real time using vital staining such as methylene blue.

 In this article, we report details of the observation of the esophagus and stomach. Further we introduce the newly developed "integrated type endocytoscopy".

 By observing the normal esophageal mucosa using the endo-cytoscopy system and methylene blue staining, we were able to visualize the cells existing on the surface of the squamous epithelium. These cells were arranged homogenous and the nucleus-cytoplasmic ratio was uniform and low. In the observation of esophageal cancer, the density of the cell increased extremely compared with the normal squamous epithelium. The cell distribution was irregular with extreme heterogeneity of the cells with nuclei of different staining, size and shape. The nucleus- cytoplasm ratio was very irregular.

 In the observation of gastric cancer, irregular and branched tubules, loss of polarity and plemorphism of the nuclei can be observed.

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