Portal Hypertension Norichika Narimiya 1 , Hisao Tajiri 1 1Department of Endoscopy, Jikei University of Medicine, Tokyo Keyword: 門脈圧亢進症 , 食道静脈瘤 , 胃静脈瘤 , portal hypertensive gastropathy , portal hypertensive colopathy pp.628-633
Published Date 2003/4/24
DOI https://doi.org/10.11477/mf.1403100923
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 Changes in hemodynamics caused by portal hypertension exert various effects on the gastrointestinal wall. In the esophagus, collateral vessels resulting from portal hypertension manifest themselves as esophageal varices on the mucosal surface. A positive red color sign indicates a high risk of bleeding from an esophageal varix. Preventive and emergency treatment options include endoscopic injection scleropathy and endoscopic variceal ligation.

 Gastric varices form in the cardia and fornix of the stomach. Once bleeding begins, profuse blood loss results, but hemostasis can be achieved by local injection of n-butyl-2-cyanoacrylate (Histoacryl). Changes in the microcirculation caused by congested blood flow of the gastrointestinal tract manifest themselves as a gastric mucosal finding known as portal hypertensive gastropathy (PHG). Similar findings in the large intestine are the mucosal changes designated as portal hypertensive colopathy and rectal varices.

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