Pseudoepitheliomatous Hyperplasia of the Esophago-Gastric Junction, Report of a Case Kousuke Fukuda 1 , Tsuneya Nakamura 1 , Takio Yokoi 2 , Takashi Suzuki 1 , Kazuhiko Ohashi 1 1Department of Gastroenterology, Aichi Cancer Center Hospital 2Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital Keyword: 食道 pseudoepitheliomatous hyperplasia 逆流性食道炎 EMR pp.755-762
Published Date 2003/4/25
DOI https://doi.org/10.11477/mf.1403100871
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 A 37-year-old man was referred to our hospital for further examination of a polypoid lesion of the esophago-gastric junction detected during screening by upper GI endoscopy. The first endoscopic examination revealed a nipple-shaped polypoid lesion at the lesser curvature of the esophago-gastric junction. The lesion continued to a reddish longitudinal shallow depression in the esophagus on its oral side. We diagnosed these lesions as reflux esophagitis and hyperplastic polyp of the esophagus. The patient was followed-up for 8 months. The second endoscopy showed no remarkable change in macroscopic appearance. However, histologic finding of the biopsy specimen taken from the depression indicated atypical squamous epithelium. Endoscopic mucosal resection was performed. Histopathology showed pseudoepitheliomatous hyperplasia of the esophagus. For diagnosis, it is important to be able to differentiate this disease and its macroscopic appearance from esophageal carcinoma.

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