Collagenous Gastritis in a Young Japanese Woman, Report of a Case Shigeki Koyama 1 , Naoko Takeda 1 , Yoshihide Fujiyama 1 , Rie Kakinoki 2 , Ryoji Kushima 2 , Hidetoshi Okabe 2 1Department of Gastroenterology, Shiga University of Medical Science, Otsu, Japan 2Department of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Japan Keyword: collagenous gastritis , collagen band pp.1082-1088
Published Date 2006/6/25
DOI https://doi.org/10.11477/mf.1403100809
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 Collagenous gastritis, with or without collagenous colitis, is a rare disorder with less than 20 cases reported in the literature. Collagenous gastritis is a distinctive disorder characterized by thickening of the subepithelial collagen band in the gastric mucosa and inflammatory cell infiltration of the lamina propria. A case of collagenous gastritis, without collagenous colitis, in a 22-year-old woman with epigastralgia is reported. Endoscopy revealed a depression area in the gastric body. Biopsy specimens showed a thickened eosinophilic band-like structure (approximately 30~70μm thick) beneath the surface epithelium. It was positive on Azan staining but negative on amyloid staining, and was accompanied by marked infiltration of mononuclear cells and eosinophilia in the lamina propria. Endoscopic and histological findings have not changed for 5 years.

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