Helicobacter pyloriに起因しないとされる胃粘膜病変の形態―胃底腺ポリープ

A Form of the Gastric Mucosal Lesions Which is not Related to Presence of Helicobacter pylori Infection―Fundic Glandular Polyps

要旨　胃底腺ポリープ80例に関して，年齢，男女差，Helicobacter pylori感染の有無，胃粘膜萎縮の程度，好発部位，ポリープの個数や形態などについて検討した．平均年齢は49.7±9.7歳であった．明らかな男女差は認められなかった．胃体部に好発し，単発の例も多発の例も認めた．内視鏡的所見は，大きさは5mm程度で，山田II型を呈し，表面は平滑，色調は周辺胃粘膜とほぼ同様であった．Helicobacter pyloriの感染率は3.75％で，胃粘膜萎縮を認めない例は95.0％と高率であった．これらの所見を認める場合には胃底腺ポリープの可能性が高い．内視鏡による病変および胃粘膜の詳細な観察が診断には大切である．

　In about 80 cases of fundic glandular polyps, we studied the characteristics of age, gender gap, presence of Helicobacter pylori infection, atrophy of gastric mucosa, favorite localization, number and form. The average age was 49.7 years old. The gender gap was not clear, but the ratio of females was increasing according to the numerical increase of the polyps. Fundic glandular polyps were present mainly in the body of the stomach. As for the endoscopic findings, the polyps had smooth surfaces and similar color to the neighboring gastric mucosa. The form and size presented Yamada II type approximately 5 mm in size. The rate of infection of Helicobacter pylori was 3.75％, and 95.0％ of the subjects did not show atrophy of the gastric mucosa. Verification of these characteristics was very likely to lead to a diagnosis of fundic glandular polyps. For the diagnosis of fundic glandular polyps, detailed endoscopic observation of the gastric mucosa is very important.