Characteristics of Gastrointestinal Tract Lesions in a Representative Immunodeficiency State:ATL/L Ikuko Iwashita 1,2 1Department of Radiology, Nishifukuoka Hospital Keyword: ATL/L , 免疫不全 , 消化管病変 , 日和見感染 , multiple malignant neo-plasms pp.1155-1171
Published Date 2005/7/25
DOI https://doi.org/10.11477/mf.1403100139
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I reviewed 191 cases of ATL/L(adult T-cell leukemia/lymphoma)for gastrointestinal lesions which develop on the basis of immunodeficiency. The macroscopic features of gastrointestinal lesions developed by ATL-cell infiltration were different among organs affected. Mixed type was most frequently seen in the stomach and multiple elevated lesions were most frequently observed in the small intestine. There was a higher tendency in ATL/L cases towards the formation of diffuse or multiple lesions than in non-ATL/L cases of malignant lymphoma of the gastrointestinal tract.

 Opportunistic infection of the digestive organs was seen in 4.2 % of the cases. Immunodeficiency caused by myelosuppression by chemotherapies or by progression of ATL/L itself was thought to be the background of opportunistic infection. It is known that a mild immunodeficiency state exists from an early stage or carrier state of HTLV-1 infection. Strongyloides infection related to this mild immunodeficiency state and the complication of cancer of other organs were also referred to.

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