Gastrointestinal Manifestations in the Immunological Deficiency State: Except the Specific Infectious Disease Mitsuyuki Murano 1 , Yosuke Abe 1 , Yutaro Egashira 2 , Atsushi Yoden 3 , Ken Narabayashi 1 , Sadaharu Noda 1 , Kumi Ishida 1 , Ken Kawakami 1 , Takanori Kuramoto 1 , Naoko Murano 1 , Eiji Umegaki 1 , Shiro Nakamura 4 , Ichiro Hirata 5 , Kazuhide Higuchi 1 1Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan 2First Department of Pathology, Osaka Medical College, Takatsuki, Japan 3Department of Pediatrics, Osaka Medical College, Takatsuki, Japan 4Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan 5Department of Gastroenterology, Fujita Health University, Toyoake, Japan Keyword: 免疫不全 , 原発性免疫不全症 , 続発性免疫不全症 , 消化管病変 pp.217-228
Published Date 2011/3/25
DOI https://doi.org/10.11477/mf.1403102148
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 In the new classification of PID(primary immunodeficiency diseases)autoimmune diseases accompanied by neither immunoregulation diseases nor predictable infectivity have been incorporated, and there are 150 or more different forms in this disease group.

 The gastrointestinal lesion of the PID presents with an infectious disease, a sprue-like lesion, various ulcerative lesions, a malignant tumor, and epithelium regeneration injuries due to recurrence, grave infection and gene defect, with the mutation to be prolonged play an important role. It is important clinically to diagnose a gastrointestinal lesion in the immunological deficiency state at an early stage, and to predict an unfavorable immunological deficiency state from a gut lesion.

 When diagnosis of a gastrointestinal lesion with immunodeficiency is made in consideration of the establishment of the type of each disease, it is important to find the visible characteristics of the gut lesions which may occur.

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