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Lung-Protective Ventilation Strategies:From ARDS to the Operating Room Shunsuke YAWATA 1 , Yusuke IIZUKA 1 1Department of Anesthesiology and Critical Care Medicine, Jichi Medical University Saitama Medical Center Keyword: postoperative pulmonary complication , PPC , lung protective ventilation , low tidal volume , positive end-expiratory pressure , PEEP , recruitment pp.5-12
Published Date 2026/1/10
DOI https://doi.org/10.18916/masui.2026010005

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  • Abstract
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 Lung-protective ventilation(LPV)strategies were originally developed to improve the outcomes of patients with acute respiratory distress syndrome(ARDS)by applying low tidal volumes(TVs)and appropriate levels of positive end-expiratory pressure(PEEP). This approach has since been extended to intraoperative ventilation in surgical patients to prevent postoperative pulmonary complications(PPCs), rather than to directly reduce mortality. Recent studies highlight additional LPV concepts such as the driving pressure(ΔP), transpulmonary pressure, and mechanical power. Although a low TV is consistently associated with a reduced risk of PPCs, the roles of high PEEP and recruitment maneuvers remain controversial, with mixed evidence regarding their effectiveness and safety. In addition, a high intraoperative Fio2 value, which had been proposed for reducing the risk of surgical site infections, has not demonstrated consistent benefit and may actually increase the PPC risk due to atelectasis. Various PPC risk prediction tools, including the ARISCAT and NSQIP calculators, help identify high-risk patients and guide perioperative care. This article provides a general overview of LPV in perioperative patient management, emphasizing the importance of individualized ventilation strategies. An evaluation of the PPC risk and the implementation of a low TV value with appropriate(and not excessive)PEEP remain key elements in optimizing surgical patients’ outcomes.


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電子版ISSN 印刷版ISSN 0021-4892 克誠堂出版

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