反復性顔面神経麻痺について—水痘帯状疱疹ウイルス抗体価および皮内反応との相関について

RECURRENT FACIAL PARALYSIS: RELATION TO VARICELLA-ZOSTER VIRUS ANTIBODY LEVELS AND SKIN TEST

　Ⅰ．はじめに

　末梢性顔面神経麻痺（以下，顔神麻痺と略す）は，時として反復することがある。最近でも諸外国ではBoddie^1），Powers^2），Werneckら^3），Abrolら^4），Mamoliら^5）などの報告がみられ，本邦においても，朴沢ら^6），小池ら^7）などがあり，われわれも7例の反復性麻痺について報告した（玉置ら^8））。

　今回，先の報告後，1977年1月より1979年3月までに，さらに6例の反復性顔神麻痺患者を経験し，水痘帯状疱疹ウイルス（varicella-zoster virus，以下VZV）抗体価，VZV皮内反応などの検査も施行したので，原因などにつき若干の考察を加え報告する。

　Six patients with recurrent facial paralysis consisted of three males and three females were treated during Jan. 1977 to March 1979. The first paralysis occurred in each patient at eleven to 48 years of age, and the interval between paralysis was one to fourteen years. Antivaricella-zoster virus (VZV) antibody levels were within normal range in all cases. VZV skin test, which seemed to associate with cell mediated immunity, was positive in these cases as same as the normal control group, but significantly differed from Hunt syndrome and Bell's palsy. The prognosis were not so good as compared with that of Bell's palsy, and recovery was complete in one, moderate in two, poor in three. Angioneurotic change of the facial nerve may be an etiology of this paralysis, but from the point of view of the cell-mediated immunity, this paralysis seems different from Bell's palsy.