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Intracranial Foreign Body Granuloma Caused by Fine Cotton Fibers:A case report Takahiro NAKAYAMA 1,2 , Katunori SHIMAZAKI 1 , Junichi ONO 1 , Katunobu OHSATO 1 , Akira YAMAURA 1 1Department of Neurosurgery, Chiba University School of Medicine Keyword: Cotton fiber , Granuloma , Astrocytoma pp.1081-1084
Published Date 1994/11/10
DOI https://doi.org/10.11477/mf.1436900941

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  • Abstract
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Reported here is a rare case of intracranial foreign body granuloma caused by fine cotton fibers originat-ing from the cotton sheet, which was used in the pre-vious Operation.

The patient was a 54-year-old woman who presented with headache and right hemiparesis. CT scan demon-strated a large enhanced tumor in the left temporal lobe. During the operation, the tumor bled easily and was hard to remove. The brain surface was covered with oxidized cellulose (Oxycell®) after the tumor was sub-totally removed. Cotton sheets (Surgical Patty®) were also used during the operation. The microfibrillar col-lagen hemostat (Avitene®) was not applied. The histo-logical diagnosis was astrocytoma. Radio-chemotherapy was given. CT and MRI on the 40th day after the op-eration, showed a large tumor in the left temporal lobe, which led to suspicions of tumor recurrence. The second operation disclosed a mass which was harder in consistence than the previous one. The histological di-agnosis was foreign body granuloma, which contained a lot of fine cotton fibers. Oxcell® was not found in it. The cotton-sheet is well documented as a cause of granuloma in the literature, but it is seldom mentioned that the foreign body granuloma is caused by cotton fi-bers, scattered in the operative fields. This case report suggests the possibility of cotton-fiber granuloma and our simple experiment indicated that a lot of cotton fi-ber might be scattered in the operative fields, if dry cotton sheets are used. These results stress that washed cotton sheets should be applied to avoid the possibility of the development of cotton-fiber foreign body granu-loma.


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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