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Clinical Study of Intracranial Pressure and Auditory Brain Stem Response in the Cases of Diffuse Axonal Injury Hiroyuki YOKOTA 1 , Hiroshi HENMI 1 , Kunihiro MASHIKO 1 , Kazuhiro YASUDA 1 , Toshlbumi OTSUKA 1 , Shiro KOBAYASHI 2 , Kouzo YAJIMA 2 , Shozo NAKAZAWA 2 1Departmcnt of Emergency and Criticad Care Medlcine, Nippon Medical School 2Department of Neurosurgery,Nippon Medicai School Keyword: Diffuse axonal Injury , Intracranial pressure , Auditory brain stem response pp.217-221
Published Date 1992/3/10
DOI https://doi.org/10.11477/mf.1436900409

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  • Abstract
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The course of intracranial pressure (ICP) and the finding of auditory brain stem response (ABR) was dis-cussed in the cases diagnosed as diffuse axonal injury (DAI) established by Gennarelli.

ICP was measured in twenty-six cases which were divided into three groups according to the course of ICP: Group (1), in which ICP remained below 20mmHg (group I, 9 cases). Group (2), in which ICP rose above 20mmHg but was controlled by therapy (group II, 8 cases). Group (3) , in which ICP rose above 20mmHg and could not be controlled by any therapies (group III, 9 cases). Glasgow outcome scale 3 months after the injury in the cases of group I and 11 was severe disability (SD) and/or persistent vegetative state (PVS), but all of the cases in group III died. The findings of serial ABR were divided into 3 groups. These were group A (2 cases) which showed normal record, group B (5 cases) which showed elonga-tion of latencies between the first and fifth waves, and group C (5 cases) in which there was no response in ABR. GOS in group A or B was SD and/or PVS, but all of the cases in group C were showen to he dead in GOS.

Our studies suggest that the level of ICP in DAI is rather higher than that published in previous reports, and the continuous measurements of ICP and serial re-cords of ABR are useful for evaluating the outcome of DAI.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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