中頭蓋底より後頭蓋窩に進展したChondromyxoid fibromaの1例

Chondromyxoid Fibroma of the Skull Base Extending from Middle Fossa to Posterior Fossa: Case report

I．はじめに

　chondromyxoid fibromaは，1948年にJaffeおよびLichtenstein^8）により1つのentityとして確立された良性の骨腫瘍である．その発生頻度は全骨腫瘍の1％以下^5,13）と非常に稀で，しかも大部分が下肢の長管骨のmetaphysisに発生する^3,5,8,13）．頭蓋骨への発生例は極めて少なく，現在までに数例の報告を見るのみである^{2,9,10,12,16-18）}．

　今回われわれは，精神症状で発症し，血小板減少を伴った，頭蓋底部の巨大なchondromyxoid fibromaの1手術治験例を経験したので，ここに報告し，文献的考察を加える．

An extremely rare case of chondromyxoid fibroma of the skull base extending from middle fossa to posterior fossa is reported.

The patient is a fourty-seven year old woman who became paranoiac four months before admission and her gait was unsteady for one month. On April 27th, 1985, she fainted and was admitted to Kanto Rosai Hospital on April 30th. She was drowsy and disorient-ed. Neurologic examination revealed left pyramidal tract signs and impaired functions of right Vth ( first and second branches ), VIth and VIIIth cranial nerves.

She was anemic and bleeding tendency due to throm-bocytopenia was also recognized.