Japanese
English
- 有料閲覧
PPV購入案内
1,320円 (1,200円+税10%) こちらは、796ページから806ページの文献です。購入には医書.jp本会員登録が必要です。
会員登録完了後に改めて上記「購入サイトへ」を選択してください。
または「購入サイトへ」選択後に「購入ログイン」、「新規会員登録」の順に進んでください。
会員登録について詳しくはをご確認ください。
- Abstract 文献概要
- 1ページ目 Look Inside
INTRODUCTION
Animal models for human neurodegenerative diseases such as Parkinson's disease are practically indispensable for research. A disease in humans presents us with a tantalizing natural experiment, but cannot and should not be manipulated, except with a view towards prevention or improvement; opportunities for examining the associated structural and biochemical changes are very limited indeed. Structural changes are usually restricted to autopsy material, with unavoidable, though variable, post mortem changes superimposed on the abnormalities existing during life. Opportunities to study early biochemical and morphological abnormalities, perhaps antedating clinical illness, are likewise extremely rare, although biochemical changes during life are becoming increasingly accessible with the use of positron imaging techniques.

Copyright © 1987, Igaku-Shoin Ltd. All rights reserved.

