妊娠に伴う網脈絡膜症について

Chorioretinopathy in pregnancy

　妊娠に合併した網脈絡膜症の2例を報告した。症例1は39歳，妊娠35週で妊娠中毒症を合併していた。両眼底後極部に散在する分葉状の浮腫状混濁病巣を認めた。帝王切開後，病変は拡大した。螢光眼底造影において初期に脈絡膜螢光の充盈欠損を，後期に脈絡膜より多発性の螢光色素漏出を認めた。症例2は32歳，妊娠24週で，臨床的に妊娠中毒症はなかった。左眼底視神経乳頭を中心に浮腫状混濁病巣とその外周に小斑状灰白色病巣の散在を認めた。本病変は妊娠中毒症発現機序における脈絡膜毛細血管循環障害に起因するものであり，臨床的妊娠中毒症を呈さずとも発症すると考える。

Two cases of chorioretinopathy in pregnancy were reported.

Case 1 was a 39 year old woman in the 35 ges-tational weeks with toxemia of pregnancy, Fundu-scopic examination revealed bilateral multi-focal lobular opaque edematous lesions at the posterior pole. Fluorescein angiography demonstrated defect of choroidal filling in the early phase and multi -focal dye leakage from choroid in the late phase.

Case 2 was a 32 year old woman in the 24 ges-tational weeks without clinical signs of toxemia of pregnancy. In funduscopic examination, opaque edematous lesion around the disc with small lobular gray white satellite lesions were observed in the left eye.

The cause of this chorioretinopathy was thought to be derived from the insufficiency of choriocapir-ally circulation caused by the mechanisms of tox-emia of pregnancy. This chorioretinopathy may be found in the case without any clinical signs of toxemia of pregnancy.