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A case of arteritic posterior ischemic optic neuropathy with increased plasma interleukin-6 levels during the follow-up Nanami Kishimoto 1,2 , Takaaki Hayashi 1 , Machiko Suda 3 , Masahiko Suzuki 3 , Tadashi Nakano 2 1Department of Ophthalmology, The Jikei University Katsushika Medical Center 2Department of Ophthalmology, The Jikei University School of Medicine 3Department of Neurology, The Jikei University Katsushika Medical Center pp.1209-1217
Published Date 2022/9/15
DOI https://doi.org/10.11477/mf.1410214495

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Abstract Objective:To report a case of arteritic posterior ischemic optic neuropathy (PION) secondary to giant cell arteritis(GCA)presenting with increased plasma interleukin-6(IL-6)levels during the follow-up.

Case:A 75-year-old woman presented with visual loss and visual-field defect in her right eye 1.5 months after right amaurosis fugax.

Findings:The corrected visual acuity was 0.07 in the right eye and 1.2 in the left eye, and the right relative afferent pupillary defect was positive. Funduscopy showed no remarkable findings, but fluorescein angiography revealed a delayed filling of choroidal vessels. A blood test showed inflammatory findings. Thickened and enhanced superficial temporal arteries were observed on the contrast-enhanced brain MRI. Finally, the patient was diagnosed with arteritic PION, secondary to GCA, underwent steroid semi-pulse therapy. The patient presented with increased plasma IL-6 levels during the follow-up.

Conclusion:It is important to diagnose macrovascular diseases associated with GCA. Increased plasma IL-6 levels were observed in arteric PION secondary to GCA.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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